Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
The three-dimensional folding of chromosomes compartmentalizes the genome and and can bring distant functional elements, such as promoters and enhancers, into close spatial proximity 2-6. Deciphering the relationship between chromosome organization and genome activity will aid in understanding genom...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
MyJove Corporation
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149993/ |