Spatial organization of RYRs and BK channels underlying the activation of STOCs by Ca2+ sparks in airway myocytes

Short-lived, localized Ca2+ events mediate Ca2+ signaling with high efficiency and great fidelity largely as a result of the close proximity between Ca2+-permeable ion channels and their molecular targets. However, in most cases, direct evidence of the spatial relationship between these two types of...

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Bibliographic Details
Main Authors: Lifshitz, Lawrence M., Carmichael, Jeffrey D., Lai, F. Anthony, Sorrentino, Vincenzo, Bellvé, Karl, Fogarty, Kevin E., ZhuGe, Ronghua
Format: Online
Language:English
Published: The Rockefeller University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149436/