Dimerumic Acid Inhibits SW620 Cell Invasion by Attenuating H2O2-Mediated MMP-7 Expression via JNK/C-Jun and ERK/C-Fos Activation in an AP-1-Dependent Manner
Reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) in the tumor microenvironment play important roles in tumor invasion and metastasis. Recently, ROS have been reported to cause a significant increase in the production and expression of matrix metalloproteinase (MMP)-7, which is closely...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Ivyspring International Publisher
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149281/ |