Epigenetics of Estrogen Receptor Signaling: Role in Hormonal Cancer Progression and Therapy
Estrogen receptor (ERα) signaling plays a key role in hormonal cancer progression. ERα is a ligand-dependent transcription factor that modulates gene transcription via recruitment to the target gene chromatin. Emerging evidence suggests that ERα signaling has the potential to contribute to epigeneti...
Main Authors: | , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Molecular Diversity Preservation International (MDPI)
2011
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147309/ |