A Novel Elevated Plus-Maze Procedure to Avoid the One-Trial Tolerance Problem
The elevated plus-maze (EPM) test is one of the most commonly used behavioral assays to evaluate anxiety-related behavior in rodents. It is an economic test (5 min duration) without prior conditioning of the animals. The critical measure for anxiety is the time spent in the open arms of the maze. A...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Frontiers Research Foundation
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146044/ |