Exploring the limits of fold discrimination by structural alignment: A large scale benchmark using decoys of known fold

Protein structure comparison by pairwise alignment is commonly used to identify highly similar substructures in pairs of proteins and provide a measure of structural similarity based on the size and geometric similarity of the match. These scores are routinely applied in analyses of protein fold spa...

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Bibliographic Details
Main Authors: Hollup, Siv Midtun, Sadowski, Michael I., Jonassen, Inge, Taylor, William R.
Format: Online
Language:English
Published: Elsevier 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145973/