c-Met recruits ICAM-1 as a coreceptor to compensate for the loss of CD44 in Cd44 null mice

c-Met recruits ICAM-1 as a coreceptor to compensate for the loss of CD44 in Cd44 null mice

CD44v6 acts as a coreceptor for the receptor tyrosine kinases c-Met and VEGFR-2. It is shown that ICAM-1 can act as a new coreceptor in CD44v6-negative tumor cells. Furthermore, ICAM-1 can substitute for CD44v6 as a coreceptor for c-Met in primary hepatocytes and in liver regeneration in Cd44 null m...

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Bibliographic Details
Main Authors: Olaku, Vivienne, Matzke, Alexandra, Mitchell, Claudia, Hasenauer, Susanne, Sakkaravarthi, Arul, Pace, Giuseppina, Ponta, Helmut, Orian-Rousseau, Véronique
Format: Online
Language:English
Published: The American Society for Cell Biology 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145552/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145552/

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