Tolerance to Non-Opioid Analgesics is Opioid Sensitive in the Nucleus Raphe Magnus

Repeated injection of opioid analgesics can lead to a progressive loss of effect. This phenomenon is known as tolerance. Several lines of investigations have shown that systemic, intraperitoneal administration or the microinjection of non-opioid analgesics, non-steroidal anti-inflammatory drugs (NSA...

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Bibliographic Details
Main Authors: Tsagareli, Merab G., Nozadze, Ivliane, Tsiklauri, Nana, Gurtskaia, Gulnaz
Format: Online
Language:English
Published: Frontiers Research Foundation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145141/