Craniosynostosis of Coronal Suture in Twist1+/− Mice Occurs Through Endochondral Ossification Recapitulating the Physiological Closure of Posterior Frontal Suture

Craniosynostosis, the premature closure of cranial suture, is a pathologic condition that affects 1/2000 live births. Saethre-Chotzen syndrome is a genetic condition characterized by craniosynostosis. The Saethre-Chotzen syndrome, which is defined by loss-of-function mutations in the TWIST gene, is...

Full description

Bibliographic Details
Main Authors: Behr, Björn, Longaker, Michael T., Quarto, Natalina
Format: Online
Language:English
Published: Frontiers Research Foundation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143731/