Bi-Directional Effect of Increasing Doses of Baclofen on Reinforcement Learning
In rodents as well as in humans, efficient reinforcement learning depends on dopamine (DA) released from ventral tegmental area (VTA) neurons. It has been shown that in brain slices of mice, GABAB-receptor agonists at low concentrations increase the firing frequency of VTA–DA neurons, while high con...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Frontiers Research Foundation
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143686/ |