Runs of Homozygosity Do Not Influence Survival to Old Age

Runs of homozygosity (ROH) are extended tracts of adjacent homozygous single nucleotide polymorphisms (SNPs) that are more common in unrelated individuals than previously thought. It has been proposed that estimating ROH on a genome-wide level, by making use of the genome-wide single nucleotide poly...

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Bibliographic Details
Main Authors: Kuningas, Maris, McQuillan, Ruth, Wilson, James F., Hofman, Albert, van Duijn, Cornelia M., Uitterlinden, André G., Tiemeier, Henning
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143169/