siRNA Knockdown of Ribosomal Protein Gene RPL19 Abrogates the Aggressive Phenotype of Human Prostate Cancer

siRNA Knockdown of Ribosomal Protein Gene RPL19 Abrogates the Aggressive Phenotype of Human Prostate Cancer

We provide novel functional data that posttranscriptional silencing of gene RPL19 using RNAi not only abrogates the malignant phenotype of PC-3M prostate cancer cells but is selective with respect to transcription and translation of other genes. Reducing RPL19 transcription modulates a subset of gen...

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Bibliographic Details
Main Authors: Bee, Alix, Brewer, Daniel, Beesley, Carol, Dodson, Andrew, Forootan, Shiva, Dickinson, Timothy, Gerard, Patricia, Lane, Brian, Yao, Sheng, Cooper, Colin S., Djamgoz, Mustafa B. A., Gosden, Christine M., Ke, Youqiang, Foster, Christopher S.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142177/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142177/

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