Moderate Long-Term Modulation of Neuropeptide Y in Hypothalamic Arcuate Nucleus Induces Energy Balance Alterations in Adult Rats

Neuropeptide Y (NPY) produced by arcuate nucleus (ARC) neurons has a strong orexigenic effect on target neurons. Hypothalamic NPY levels undergo wide-ranging oscillations during the circadian cycle and in response to fasting and peripheral hormones (from 0.25 to 10-fold change). The aim of the prese...

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Main Authors: Sousa-Ferreira, Lígia, Garrido, Manuel, Nascimento-Ferreira, Isabel, Nobrega, Clévio, Santos-Carvalho, Ana, Álvaro, Ana Rita, Rosmaninho-Salgado, Joana, Kaster, Manuella, Kügler, Sebastian, Pereira de Almeida, Luís, Cavadas, Claudia
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142146/