Inositol hexakisphosphate kinase 1 (InsP6K1) regulates neutrophil function in innate immunity by inhibiting PtdIns(3,4,5)P3 signaling

Inositol hexakisphosphate kinase 1 (InsP6K1) regulates neutrophil function in innate immunity by inhibiting PtdIns(3,4,5)P3 signaling

Inositol phosphates (InsP) are widely produced throughout animal and plant tissues. Diphosphoinositol pentakisphosphate (InsP7) contains an energetic pyrophosphate bond. Here, we demonstrate that disruption of InsP6K1, one of the three mammalian InsP6Ks that convert InsP6 to InsP7, confers enhanced...

Full description

Bibliographic Details
Main Authors: Prasad, Amit, Jia, Yonghui, Chakraborty, Anutosh, Li, Yitang, Jain, Supriya K., Zhong, Jia, Roy, Saurabh Ghosh, Loison, Fabien, Mondal, Subhanjan, Sakai, Jiro, Blanchard, Catlyn, Snyder, Solomon H., Luo, Hongbo R.
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140608/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140608/

Similar Items