A biological pathway linking inflammation and depression: activation of indoleamine 2,3-dioxygenase
This article highlights the evidence linking depression to increased inflammatory drive and explores putative mechanisms for the association by reviewing both preclinical and clinical literature. The enzyme indoleamine 2,3-dioxygenase is induced by proinflammatory cytokines and may form a link betwe...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Dove Medical Press
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140295/ |