Genomic Analysis of Hepatitis B Virus Reveals Antigen State and Genotype as Sources of Evolutionary Rate Variation

Hepatitis B virus (HBV) genomes are small, semi-double-stranded DNA circular genomes that contain alternating overlapping reading frames and replicate through an RNA intermediary phase. This complex biology has presented a challenge to estimating an evolutionary rate for HBV, leading to difficulties...

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Bibliographic Details
Main Authors: Harrison, Abby, Lemey, Philippe, Hurles, Matthew, Moyes, Chris, Horn, Susanne, Pryor, Jan, Malani, Joji, Supuri, Mathias, Masta, Andrew, Teriboriki, Burentau, Toatu, Tebuka, Penny, David, Rambaut, Andrew, Shapiro, Beth
Format: Online
Language:English
Published: Molecular Diversity Preservation International (MDPI) 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136878/