Galectin-3C Inhibits Tumor Growth and Increases the Anticancer Activity of Bortezomib in a Murine Model of Human Multiple Myeloma

Galectin-3 is a human lectin involved in many cellular processes including differentiation, apoptosis, angiogenesis, neoplastic transformation, and metastasis. We evaluated galectin-3C, an N-terminally truncated form of galectin-3 that is thought to act as a dominant negative inhibitor, as a potenti...

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Bibliographic Details
Main Authors: Mirandola, Leonardo, Yu, Yuefei, Chui, Kitty, Jenkins, Marjorie R., Cobos, Everardo, John, Constance M., Chiriva-Internati, Maurizio
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135605/