Hierarchical regulation of mRNA partitioning between the cytoplasm and the endoplasmic reticulum of mammalian cells
This study reveals that mRNAs are partitioned between the cytosol and endoplasmic reticulum (ER) compartments in a hierarchical manner and identifies a prominent role for the ER in global protein synthesis. Two modes of mRNA association with the ER are defined: ribosome dependent and ribosome indepe...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135488/ |