A contractile actomyosin network linked to adherens junctions by Canoe/afadin helps drive convergent extension

Coordination of adhesion and the actin cytoskeleton is critical in morphogenesis. Drosophila germband extension is a model for convergent extension. Canoe/afadin is found to have a novel role in this process. It helps to coordinate a contractile apical actomyosin network with cell shape change and r...

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Bibliographic Details
Main Authors: Sawyer, Jessica K., Choi, Wangsun, Jung, Kuo-Chen, He, Li, Harris, Nathan J., Peifer, Mark
Format: Online
Language:English
Published: The American Society for Cell Biology 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135475/