CIN85 drives B cell responses by linking BCR signals to the canonical NF-κB pathway

CIN85 transduces B cell receptor signals to IKK-β, and its expression in B cells is essential for T cell–independent type II antibody responses in mice.

Bibliographic Details
Main Authors: Kometani, Kohei, Yamada, Takayuki, Sasaki, Yoshiteru, Yokosuka, Tadashi, Saito, Takashi, Rajewsky, Klaus, Ishiai, Masamichi, Hikida, Masaki, Kurosaki, Tomohiro
Format: Online
Language:English
Published: The Rockefeller University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135365/