Swinholide J, a Potent Cytotoxin from the Marine Sponge Theonella swinhoei

In our ongoing search for new pharmacologically active leads from Solomon organisms, we have examined the sponge Theonella swinhoei. Herein we report the isolation and structure elucidation of swinholide A (1) and one new macrolide, swinholide J (2). Swinholide J is an unprecedented asymmetric 44-me...

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Bibliographic Details
Main Authors: De Marino, Simona, Festa, Carmen, D’Auria, Maria Valeria, Cresteil, Thierry, Debitus, Cecile, Zampella, Angela
Format: Online
Language:English
Published: Molecular Diversity Preservation International 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131564/