A Workflow for Global Sensitivity Analysis of PBPK Models
Physiologically based pharmacokinetic (PBPK) models have a potentially significant role in the development of a reliable predictive toxicity testing strategy. The structure of PBPK models are ideal frameworks into which disparate in vitro and in vivo data can be integrated and utilized to translate...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Research Foundation
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128931/ |