Glioblastoma motility occurs in the absence of actin polymer

Human glioblastoma cells are motile in the absence of intact actin polymers, following suppression of actin assembly by specific inhibitors. On the other hand, suppression of microtubules completely blocks motility. These results are clearly divergent from the standard model of actin-based cell moti...

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Bibliographic Details
Main Authors: Panopoulos, Andreas, Howell, Michael, Fotedar, Rati, Margolis, Robert L.
Format: Online
Language:English
Published: The American Society for Cell Biology 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128524/