Cyclic di-GMP is Essential for the Survival of the Lyme Disease Spirochete in Ticks

Cyclic dimeric GMP (c-di-GMP) is a bacterial second messenger that modulates many biological processes. Although its role in bacterial pathogenesis during mammalian infection has been documented, the role of c-di-GMP in a pathogen's life cycle within a vector host is less understood. The enzoot...

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Bibliographic Details
Main Authors: He, Ming, Ouyang, Zhiming, Troxell, Bryan, Xu, Haijun, Moh, Akira, Piesman, Joseph, Norgard, Michael V., Gomelsky, Mark, Yang, X. Frank
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128128/