Multiple Loci Are Associated with White Blood Cell Phenotypes

White blood cell (WBC) count is a common clinical measure from complete blood count assays, and it varies widely among healthy individuals. Total WBC count and its constituent subtypes have been shown to be moderately heritable, with the heritability estimates varying across cell types. We studied 1...

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Bibliographic Details
Main Authors: Nalls, Michael A., Couper, David J., Tanaka, Toshiko, van Rooij, Frank J. A., Chen, Ming-Huei, Smith, Albert V., Toniolo, Daniela, Zakai, Neil A., Yang, Qiong, Greinacher, Andreas, Wood, Andrew R., Garcia, Melissa, Gasparini, Paolo, Liu, Yongmei, Lumley, Thomas, Folsom, Aaron R., Reiner, Alex P., Gieger, Christian, Lagou, Vasiliki, Felix, Janine F., Völzke, Henry, Gouskova, Natalia A., Biffi, Alessandro, Döring, Angela, Völker, Uwe, Chong, Sean, Wiggins, Kerri L., Rendon, Augusto, Dehghan, Abbas, Moore, Matt, Taylor, Kent, Wilson, James G., Lettre, Guillaume, Hofman, Albert, Bis, Joshua C., Pirastu, Nicola, Fox, Caroline S., Meisinger, Christa, Sambrook, Jennifer, Arepalli, Sampath, Nauck, Matthias, Prokisch, Holger, Stephens, Jonathan, Glazer, Nicole L., Cupples, L. Adrienne, Okada, Yukinori, Takahashi, Atsushi, Kamatani, Yoichiro, Matsuda, Koichi, Tsunoda, Tatsuhiko, Tanaka, Toshihiro, Kubo, Michiaki, Nakamura, Yusuke, Yamamoto, Kazuhiko, Kamatani, Naoyuki, Stumvoll, Michael, Tönjes, Anke, Prokopenko, Inga, Illig, Thomas, Patel, Kushang V., Garner, Stephen F., Kuhnel, Brigitte, Mangino, Massimo, Oostra, Ben A., Thein, Swee Lay, Coresh, Josef, Wichmann, H.-Erich, Menzel, Stephan, Lin, JingPing, Pistis, Giorgio, Uitterlinden, André G., Spector, Tim D., Teumer, Alexander, Eiriksdottir, Gudny, Gudnason, Vilmundur, Bandinelli, Stefania, Frayling, Timothy M., Chakravarti, Aravinda, van Duijn, Cornelia M., Melzer, David, Ouwehand, Willem H., Levy, Daniel, Boerwinkle, Eric, Singleton, Andrew B., Hernandez, Dena G., Longo, Dan L., Soranzo, Nicole, Witteman, Jacqueline C. M., Psaty, Bruce M., Ferrucci, Luigi, Harris, Tamara B., O'Donnell, Christopher J., Ganesh, Santhi K.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128114/