Substantial Histone Reduction Modulates Genomewide Nucleosomal Occupancy and Global Transcriptional Output

Substantial Histone Reduction Modulates Genomewide Nucleosomal Occupancy and Global Transcriptional Output

The basic unit of genome packaging is the nucleosome, and nucleosomes have long been proposed to restrict DNA accessibility both to damage and to transcription. Nucleosome number in cells was considered fixed, but recently aging yeast and mammalian cells were shown to contain fewer nucleosomes. We s...

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Bibliographic Details
Main Authors: Celona, Barbara, Weiner, Assaf, Di Felice, Francesca, Mancuso, Francesco M., Cesarini, Elisa, Rossi, Riccardo L., Gregory, Lorna, Baban, Dilair, Rossetti, Grazisa, Grianti, Paolo, Pagani, Massimiliano, Bonaldi, Tiziana, Ragoussis, Jiannis, Friedman, Nir, Camilloni, Giorgio, Bianchi, Marco E., Agresti, Alessandra
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125158/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125158/

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