Polymorphisms of the prion protein gene and their effects on litter size and risk evaluation for scrapie in Chinese Hu sheep

It is well known that scrapie is a fatal, neurodegenerative disease in sheep and goat, which belongs to the group of transmissible spongiform encephalopathies (TSEs) or prion diseases. It has been confirmed that the polymorphisms of prion protein gene (PRNP) at codons 136, 154, and 171 have strong r...

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Bibliographic Details
Main Authors: Guan, Feng, Pan, Lei, Li, Jie, Tang, Hong, Zhu, Cheng, Shi, Guoqing
Format: Online
Language:English
Published: Springer US 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124648/