Multiple Oxygen Tension Environments Reveal Diverse Patterns of Transcriptional Regulation in Primary Astrocytes

The central nervous system normally functions at O2 levels which would be regarded as hypoxic by most other tissues. However, most in vitro studies of neurons and astrocytes are conducted under hyperoxic conditions without consideration of O2-dependent cellular adaptation. We analyzed the reactivity...

Full description

Bibliographic Details
Main Authors: Chadwick, Wayne, Boyle, John P., Zhou, Yu, Wang, Liyun, Park, Sung-Soo, Martin, Bronwen, Wang, Rui, Becker, Kevin G., Wood, William H., Zhang, Yongqing, Peers, Chris, Maudsley, Stuart
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124552/