Chlamydia trachomatis Vaccine Research through the Years

Chlamydia trachomatis is a Gram-negative obligate intracellular bacterium. It is the leading cause of bacterial sexual transmitted infections (STIs). World Health Organization figures estimated that over 90 million new cases of genital C. trachomatis infections occur worldwide each year. A vaccinat...

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Main Authors: Schautteet, Katelijn, De Clercq, Evelien, Vanrompay, Daisy
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124257/
id pubmed-3124257
recordtype oai_dc
spelling pubmed-31242572011-07-11 Chlamydia trachomatis Vaccine Research through the Years Schautteet, Katelijn De Clercq, Evelien Vanrompay, Daisy Review Article Chlamydia trachomatis is a Gram-negative obligate intracellular bacterium. It is the leading cause of bacterial sexual transmitted infections (STIs). World Health Organization figures estimated that over 90 million new cases of genital C. trachomatis infections occur worldwide each year. A vaccination program is considered to be the best approach to reduce the prevalence of C. trachomatis infections, as it would be much cheaper and have a greater impact on controlling C. trachomatis infections worldwide rather than a screening program or treating infections with antibiotics. Currently, there are no vaccines available which effectively protect against a C. trachomatis genital infection despite the many efforts that have been made throughout the years. In this paper, the many attempts to develop a protective vaccine against a genital C. trachomatis infection will be reviewed. Hindawi Publishing Corporation 2011 2011-06-26 /pmc/articles/PMC3124257/ /pubmed/21747646 http://dx.doi.org/10.1155/2011/963513 Text en Copyright © 2011 Katelijn Schautteet et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Schautteet, Katelijn
De Clercq, Evelien
Vanrompay, Daisy
spellingShingle Schautteet, Katelijn
De Clercq, Evelien
Vanrompay, Daisy
Chlamydia trachomatis Vaccine Research through the Years
author_facet Schautteet, Katelijn
De Clercq, Evelien
Vanrompay, Daisy
author_sort Schautteet, Katelijn
title Chlamydia trachomatis Vaccine Research through the Years
title_short Chlamydia trachomatis Vaccine Research through the Years
title_full Chlamydia trachomatis Vaccine Research through the Years
title_fullStr Chlamydia trachomatis Vaccine Research through the Years
title_full_unstemmed Chlamydia trachomatis Vaccine Research through the Years
title_sort chlamydia trachomatis vaccine research through the years
description Chlamydia trachomatis is a Gram-negative obligate intracellular bacterium. It is the leading cause of bacterial sexual transmitted infections (STIs). World Health Organization figures estimated that over 90 million new cases of genital C. trachomatis infections occur worldwide each year. A vaccination program is considered to be the best approach to reduce the prevalence of C. trachomatis infections, as it would be much cheaper and have a greater impact on controlling C. trachomatis infections worldwide rather than a screening program or treating infections with antibiotics. Currently, there are no vaccines available which effectively protect against a C. trachomatis genital infection despite the many efforts that have been made throughout the years. In this paper, the many attempts to develop a protective vaccine against a genital C. trachomatis infection will be reviewed.
publisher Hindawi Publishing Corporation
publishDate 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124257/
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