Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component

The hallmark of tuberculosis (TB) is the formation of granulomas, which are clusters of infected macrophages surrounded by additional macrophages, neutrophils and lymphocytes. Although it has long been thought that granulomas are beneficial for the host, there is evidence that mycobacteria also prom...

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Bibliographic Details
Main Authors: Stoop, Esther J. M., Schipper, Tim, Rosendahl Huber, Sietske K., Nezhinsky, Alexander E., Verbeek, Fons J., Gurcha, Sudagar S., Besra, Gurdyal S., Vandenbroucke-Grauls, Christina M. J. E., Bitter, Wilbert, van der Sar, Astrid M.
Format: Online
Language:English
Published: The Company of Biologists Limited 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124061/