MMP-2 mediates mesenchymal stem cell tropism towards medulloblastoma tumors

Matrix metalloproteinases (MMPs) are a family of proteinases known to play a role in cell migration. In the present study, we evaluated the role of MMP-2 on tropism of human cord blood derived stem cells (hUCBSCs) in a human medulloblastoma tumor model. Consequences of MMP-2 inhibition on stem cell...

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Bibliographic Details
Main Authors: Bhoopathi, Praveen, Chetty, Chandramu, Gogineni, Venkateswara Rao, Gujrati, Meena, Dinh, Dzung H., Rao, Jasti S., Lakka, Sajani S.
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123681/