TREEGL: reverse engineering tree-evolving gene networks underlying developing biological lineages

Motivation: Estimating gene regulatory networks over biological lineages is central to a deeper understanding of how cells evolve during development and differentiation. However, one challenge in estimating such evolving networks is that their host cells not only contiguously evolve, but also branch...

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Bibliographic Details
Main Authors: Parikh, Ankur P., Wu, Wei, Curtis, Ross E., Xing, Eric P.
Format: Online
Language:English
Published: Oxford University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117339/