Predicting Protein Folds with Fold-Specific PSSM Libraries

Accurately assigning folds for divergent protein sequences is a major obstacle to structural studies. Herein, we outline an effective method for fold recognition using sets of PSSMs, each of which is constructed for different protein folds. Our analyses demonstrate that FSL (Fold-specific Position S...

Full description

Bibliographic Details
Main Authors: Hong, Yoojin, Chintapalli, Sree Vamsee, Ko, Kyung Dae, Bhardwaj, Gaurav, Zhang, Zhenhai, van Rossum, Damian, Patterson, Randen L.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116844/