OSBP-Related Protein 8 (ORP8) Regulates Plasma and Liver Tissue Lipid Levels and Interacts with the Nucleoporin Nup62
We earlier identified OSBP-related protein 8 (ORP8) as an endoplasmic reticulum oxysterol-binding protein implicated in cellular lipid homeostasis. We now investigated its action in hepatic cells in vivo and in vitro. Adenoviral overexpression of ORP8 in mouse liver induced a decrease of cholesterol...
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2011
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115989/ |