OSBP-Related Protein 8 (ORP8) Regulates Plasma and Liver Tissue Lipid Levels and Interacts with the Nucleoporin Nup62

We earlier identified OSBP-related protein 8 (ORP8) as an endoplasmic reticulum oxysterol-binding protein implicated in cellular lipid homeostasis. We now investigated its action in hepatic cells in vivo and in vitro. Adenoviral overexpression of ORP8 in mouse liver induced a decrease of cholesterol...

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Bibliographic Details
Main Authors: Zhou, Tianhong, Li, Shiqian, Zhong, Wenbin, Vihervaara, Terhi, Béaslas, Olivier, Perttilä, Julia, Luo, Wei, Jiang, Yingliang, Lehto, Markku, Olkkonen, Vesa M., Yan, Daoguang
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115989/