Sequence specificity is obtained from the majority of modular C2H2 zinc-finger arrays

C2H2 zinc fingers (C2H2-ZFs) are the most prevalent type of vertebrate DNA-binding domain, and typically appear in tandem arrays (ZFAs), with sequential C2H2-ZFs each contacting three (or more) sequential bases. C2H2-ZFs can be assembled in a modular fashion, providing one explanation for their rema...

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Bibliographic Details
Main Authors: Lam, Kathy N., van Bakel, Harm, Cote, Atina G., van der Ven, Anton, Hughes, Timothy R.
Format: Online
Language:English
Published: Oxford University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113560/