Type III Secretion Is Essential for the Rapidly Fatal Diarrheal Disease Caused by Non-O1, Non-O139 Vibrio cholerae

Cholera is a severe diarrheal disease typically caused by O1 serogroup strains of Vibrio cholerae. The pathogenicity of all pandemic V. cholerae O1 strains relies on two critical virulence factors: cholera toxin, a potent enterotoxin, and toxin coregulated pilus (TCP), an intestinal colonization fac...

Full description

Bibliographic Details
Main Authors: Shin, Ok S., Tam, Vincent C., Suzuki, Masato, Ritchie, Jennifer M., Bronson, Roderick T., Waldor, Matthew K., Mekalanos, John J.
Format: Online
Language:English
Published: American Society of Microbiology 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111608/