Francisella Tularensis Blue–Gray Phase Variation Involves Structural Modifications of Lipopolysaccharide O-Antigen, Core and Lipid A and Affects Intramacrophage Survival and Vaccine Efficacy
Francisella tularensis is a CDC Category A biological agent and a potential bioterrorist threat. There is no licensed vaccine against tularemia in the United States. A long-standing issue with potential Francisella vaccines is strain phase variation to a gray form that lacks protective capability in...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Frontiers Research Foundation
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109528/ |