The Degenerating Substantia Nigra as a Susceptible Region for Gene Transfer-Mediated Inflammation
Parkinson's disease (PD) is characterized by the progressive degeneration of neurons in the substantia nigra pars compacta (SN). The naïve SN is highly susceptible to inflammation. In addition, microglial activation in the degenerating SN displays distinct characteristics that increase the reac...
| Main Authors: | , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
SAGE-Hindawi Access to Research
2011
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109520/ |