Host-Mediated Post-Translational Prenylation of Novel Dot/Icm-Translocated Effectors of Legionella Pneumophila

The Dot/Icm type IV translocated Ankyrin B (AnkB) effector of Legionella pneumophila is modified by the host prenylation machinery that anchors it into the outer leaflet of the Legionella-containing vacuole (LCV), which is essential for biological function of the effector in vitro and in vivo. Preny...

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Bibliographic Details
Main Authors: Price, Christopher T. D., Jones, Snake C., Amundson, Karen E., Kwaik, Yousef Abu
Format: Online
Language:English
Published: Frontiers Research Foundation 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109360/