The Role of the Francisella Tularensis Pathogenicity Island in Type VI Secretion, Intracellular Survival, and Modulation of Host Cell Signaling

Francisella tularensis is a highly virulent gram-negative intracellular bacterium that causes the zoonotic disease tularemia. Essential for its virulence is the ability to multiply within host cells, in particular monocytic cells. The bacterium has developed intricate means to subvert host immune me...

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Bibliographic Details
Main Authors: Bröms, Jeanette E., Sjöstedt, Anders, Lavander, Moa
Format: Online
Language:English
Published: Frontiers Research Foundation 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109350/