A Better Anti-Diabetic Recombinant Human Fibroblast Growth Factor 21 (rhFGF21) Modified with Polyethylene Glycol

As one of fibroblast growth factor (FGF) family members, FGF21 has been extensively investigated for its potential as a drug candidate to combat metabolic diseases. In the present study, recombinant human FGF21 (rhFGF21) was modified with polyethylene glycol (PEGylation) in order to increase its in...

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Bibliographic Details
Main Authors: Huang, Zhifeng, Wang, Huiyan, Lu, Meifei, Sun, Chuanchuan, Wu, Xiaoping, Tan, Yi, Ye, Chaohui, Zhu, Guanghui, Wang, Xiaojie, Cai, Lu, Li, Xiaokun
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108960/