Differential regulation of diacylglycerol kinase isoform in human failing hearts

Evidence from several studies indicates the importance of Gαq protein-coupled receptor (GPCR) signaling pathway, which includes diacylglycerol (DAG), and protein kinase C, in the development of heart failure. DAG kinase (DGK) acts as an endogenous regulator of GPCR signaling pathway by catalyzing an...

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Bibliographic Details
Main Authors: Bilim, Olga, Shishido, Tetsuro, Toyama, Shuji, Suzuki, Satoshi, Sasaki, Toshiki, Kitahara, Tatsuro, Sadahiro, Mitsuaki, Takeishi, Yasuchika, Kubota, Isao
Format: Online
Language:English
Published: BioMed Central 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108920/