TGF-β-induced IRAK-M Expression in Tumor Associated Macrophages Regulates Lung Tumor Growth
Tumor associated macrophages (TAMs) constitute a major component of the immune cell infiltrate observed in the tumor microenvironment (TME). Factors present in the TME including TGF-β, allow tumors to circumvent host mediated immune responses to promote tumor progression. However, the molecular mech...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102782/ |