TGF-β-induced IRAK-M Expression in Tumor Associated Macrophages Regulates Lung Tumor Growth

Tumor associated macrophages (TAMs) constitute a major component of the immune cell infiltrate observed in the tumor microenvironment (TME). Factors present in the TME including TGF-β, allow tumors to circumvent host mediated immune responses to promote tumor progression. However, the molecular mech...

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Bibliographic Details
Main Authors: Standiford, Theodore J., Kuick, Rork, Bhan, Urvashi, Chen, Jun, Newstead, Michael, Keshamouni, Venkateshwar G.
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102782/