Population Structure of Invasive Streptococcus pneumoniae in the Netherlands in the Pre-Vaccination Era Assessed by MLVA and Capsular Sequence Typing

The introduction of nationwide pneumococcal vaccination may lead to serotype replacement and the emergence of new variants that have expanded their genetic repertoire through recombination. To monitor alterations in the pneumococcal population structure, we have developed and utilized Capsular Seque...

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Bibliographic Details
Main Authors: Elberse, Karin E. M., van de Pol, Ingrid, Witteveen, Sandra, van der Heide, Han G. J., Schot, Corrie S., van Dijk, Anita, van der Ende, Arie, Schouls, Leo M.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102707/