Emerging role of carfilzomib in treatment of relapsed and refractory lymphoid neoplasms and multiple myeloma

Proteasome inhibition forms the cornerstone of antimyeloma therapy. The first-in-class proteasome inhibitor, bortezomib, either alone or in combination with other chemotherapeutic agents, induces high overall response rates and response qualities in patients with clinically and molecularly defined h...

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Bibliographic Details
Main Authors: Jain, Salvia, Diefenbach, Catherine, Zain, Jasmine, O’Connor, Owen A
Format: Online
Language:English
Published: Dove Medical Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102580/