Physiology and pathophysiology of matrix metalloproteases

Matrix metalloproteases (MMPs) comprise a family of enzymes that cleave protein substrates based on a conserved mechanism involving activation of an active site-bound water molecule by a Zn2+ ion. Although the catalytic domain of MMPs is structurally highly similar, there are many differences with r...

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Bibliographic Details
Main Authors: Klein, T., Bischoff, R.
Format: Online
Language:English
Published: Springer Vienna 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102199/