Requirement of Replication Checkpoint Protein Kinases Mec1/Rad53 for Postreplication Repair in Yeast
DNA lesions in the template strand block the replication fork. In Saccharomyces cerevisiae, replication through DNA lesions occurs via a Rad6/Rad18-dependent pathway where lesions can be bypassed by the action of translesion synthesis (TLS) DNA polymerases η and ζ or by Rad5-mediated template switch...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
American Society of Microbiology
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101783/ |