Dynamics of epileptiform activity in mouse hippocampal slices

Increase of the extracellular K +  concentration mediates seizure-like synchronized activities in vitro and was proposed to be one of the main factors underlying epileptogenesis in some types of seizures in vivo. While underlying biophysical mechanisms clearly involve cell depolarization and overall...

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Bibliographic Details
Main Authors: Filatov, Gregory, Krishnan, Giri P., Rulkov, Nikolai F., Bazhenov, Maxim
Format: Online
Language:English
Published: Springer Netherlands 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101328/