Feasibility of Repurposing the Polyanionic Microbicide, PPCM, for Prophylaxis against HIV Transmission during ART

HIV-serodiscordant couples wishing to conceive often seek assisted reproduction, during which spermatozoa from infected men are washed to minimize the risk of HIV transmission to partner and fetus. We sought to improve this method by adding a microbicide, PPCM, as an HIV prophylactic. HIV-1 (BaL) in...

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Bibliographic Details
Main Authors: Anderson, Robert A., Brown, David, Jackson, Erin M., Feathergill, Kenneth A., Bremer, James W., Morack, Ralph, Rawlins, Richard G.
Format: Online
Language:English
Published: International Scholarly Research Network 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099743/