AAV Exploits Subcellular Stress Associated with Inflammation, Endoplasmic Reticulum Expansion, and Misfolded Proteins in Models of Cystic Fibrosis

Barriers to infection act at multiple levels to prevent viruses, bacteria, and parasites from commandeering host cells for their own purposes. An intriguing hypothesis is that if a cell experiences stress, such as that elicited by inflammation, endoplasmic reticulum (ER) expansion, or misfolded prot...

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Bibliographic Details
Main Authors: Johnson, Jarrod S., Gentzsch, Martina, Zhang, Liqun, Ribeiro, Carla M. P., Kantor, Boris, Kafri, Tal, Pickles, Raymond J., Samulski, R. Jude
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098238/